Contact Information

Author
  • Irv Levy
  • Professor
  • Chemistry
  • Gordon College
  • 255 Grapevine Road
  • Wenham, MA 01984
Email
Phone
(978) 867 - 4877
Website

Zeolite-Catalyzed Multicomponent Reaction: Preparation of a β–Acetamido Ketone

Laboratory Procedures (PDF)

Author Contact: irv.levy@gordon.edu

Summary

A multicomponent reaction ("MCR" for short) is a one-step reaction that combines two or more reagents to form an end product. Since an MCR forms a product in one step, it generates considerably less waste than a comparable multi-step synthesis. Consequently, from the point of view of green chemistry, MCRs constitute a very useful class of tools for the synthesis of new chemicals. Here is presented an MCR synthesis of a β-acetamido ketone, with zeolite catalysis.

Summary prepared August 2007 by Irvin Levy, Department of Chemistry, Gordon College.

Source

Wetter, E.; Levy, I. J.; Kay, R. Zeolite-Catalyzed Multicomponent Reaction: Preparation of a β–Acetamido Ketone, Chemistry, Gordon College, 2007

Category Descriptors

Chemistry Concepts
  • Aldehydes/Ketones
  • Carbonyl Chemistry
  • Catalysis
Laboratory Techniques
  • Assembly of Reaction Apparatus
  • Heating and Cooling Methods
  • Measuring Mass and Volume
  • Melting Points and Melting Ranges
  • Vacuum Filtration
Green Chemistry Principles
  • Avoid Chemical Derivatives
  • Prevent Waste
  • Use Catalysts
Chemistry Subdiscipline
  • Organic Chemistry
Target Audience
  • Colleges/Universities
Source
  • Original Contributions - unpublished