A multicomponent reaction ("MCR" for short) is a one-step reaction that combines two or more reagents to form an end product. Since an MCR forms a product in one step, it generates considerably less waste than a comparable multi-step synthesis. Consequently, from the point of view of green chemistry, MCRs constitute a very useful class of tools for the synthesis of new chemicals. Here is presented an MCR synthesis of a β-acetamido ketone, with zeolite catalysis.
Summary prepared August 2007 by Irvin Levy, Department of Chemistry, Gordon College.
Wetter, E.; Levy, I. J.; Kay, R. Zeolite-Catalyzed Multicomponent Reaction: Preparation of a β–Acetamido Ketone, Chemistry, Gordon College, 2007