Kwang-Ting Liu, Department of Chemistry, Department of Chemistry, National Taiwan University, 1 Section 4, Rossevelt Road, Taipei, 106, Taiwan
ABSTRACT: Because the textbooks for sophomore organic chemistry, written by American authors, used at National Taiwan University had paid little attention to the topics related to the sustainable development, supplemental materials were used in lecturing by the present author since the fall semester of 2003. The twelve principles by Anastas and Warner, and the twelve more principles by Winterton were consulted to select and to implant appropriate subjects. Microwave radiation was introduced as an alternative energy source to promote organic reactions. Greenhouse effect and/or the depletion of ozone layer due to organic reactions and compounds were mentioned. In addition to the commonly used organic media, reactions in water or supercritical fluid carbon dioxide, or under solvent-free condition were described. The use of environmentally benign catalysts and reagents was suggested to employ whenever applicable. Specific examples, such as Baeyer-Villiger oxidation, Friedel-Crafts acylation and Knoevenagel reaction, were given to illustrate the scope of green chemical reactions. The advantage and disadvantage of emphasizing the chemistry of sustainability in the teaching of sophomore organic chemistry will also be discussed.